ElixR is the world’s first cocktail (or mocktail) mix to combine a low calorie, tasty mixer with supplements to support your everyday health and your recovery after a fun time.
Our CEO, Laura Hunter, is known for her high quality inventions and innovations in the beauty industry. Laura's first invention in the supplement industry is no different. She set out to create a low calorie, caffeine free cocktail (or mocktail) mixer that is part of a healthy lifestyle by providing support in hydration along with the liver, brain, and the rest of the body. She believed drinking can be both fun and responsible, and ElixR was designed with that mission in mind.
At Tori Belle, we take great pride in creating products that are the best in the world, and ElixR is both the most effective & highest quality product of its kind on the market.
What Makes ElixR Different?
We've put together a list of the featured ingredients in ElixR along with a deep dive of supporting information and excerpts from scientific studies and articles so that you can read for yourself what ElixR can do for you!
As always, if you’re going to drink, please drink legally and responsibly.
*Blog entries are for your information only and are not intended as medical advice. Because everyone is different, you should work with your medical professional to determine what’s best for you.*
DHM
Derived from the Japanese Raisin tree, studies have found that DHM used as a dietary supplement can help support liver function.
“We know DHM helps the body to metabolize alcohol faster, but how does it work? We found it activates a cascade of mechanisms that erase alcohol from the body very quickly,” said Jing Liang, a research professor of clinical pharmacy and the corresponding author of the study. (The study appears in Alcoholism: Clinical and Experimental Research.)
Among other significant effects, the scientists found that DHM:
- Triggered the liver to produce more ethanol-gobbling enzymes, including alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH).
- Boosted the efficiency of ADH and ALDH, enabling the enzymes to convert ethanol into simpler forms the body can eliminate easier.
- Reduced lipid (fat) accumulation in liver tissue. Heavy doses of alcohol can negatively affect the liver’s metabolism, leading to an accumulation of fat, increased stress and the eventual progression to liver diseases such as cirrhosis.
- Reduced inflammatory agents, called cytokines. Excessive alcohol leads to the release of cytokines in the liver, which contributes to cellular damage to the liver and other organs.
“In total, these findings support the utility of DHM as a dietary supplement to reduce ethanol-induced liver injury via changes in lipid metabolism, enhancement of ethanol metabolism and suppressing inflammation responses to promote liver health,” the study said. “This line of research suggests that DHM acts on multiple pathways to promote liver health and counteract ethanol injury.”
Excerpts from: https://news.usc.edu/166789/hangover-remedy-dhm-liver-protection-usc-study/
Source:
Vitamin C
Supports your overall health and immune system.
“Booze does a pretty good job of zapping the body’s store of needed minerals, and Vitamin C is no exception. Even so, while alcohol depletes Vitamin C in body tissues, it can quickly be restored with supplements for positive health results.”
“Having a healthy dose of Vitamin C in your system before and after drinking may prevent or reduce the severity of side effects by speeding up the metabolism of alcohol by the liver. Alcoholics may also benefit from keeping up their Vitamin C intake as it can reduce alcohol cravings.”
Excerpts from: https://www.drinkwel.com/blogs/drinkwel-blog/24645761-vitamin-c-and-alcohol?_pos=1&_sid=6af5e98b0&_ss=r
Sources:
- https://nutrition.bmj.com/content/1/1/17
- https://ccforum.biomedcentral.com/articles/10.1186/s13054-019-2435-4
Biotin
Supports your overall health and immune system.
Biotin is an essential B vitamin that helps the body get energy and nutrients from carbohydrates, proteins, and fats. Anecdotal claims that biotin can aid hair growth are common, and its popularity among consumers is high. Additionally, some studies have suggested links between biotin deficiencies and alopecia.
Factors that can contribute to biotin deficiencies include:
- Pregnancy
- Malnutrition
- long-term use of some medications
- gastrointestinal conditions that prevent the absorption of biotin
- use of alcohol or intravenous drugs
- smoking
Sources:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989391/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582478/
- https://www.newswise.com/articles/chronic-alcohol-consumption-inhibits-intestinal-absorption-of-vitamin-b7-may-lead-to-deficiency
Potassium/Sodium
Supports hydration.
Alcohol is incredibly dehydrating because it inhibits the hormone vasopressin1 2, which helps your kidneys reabsorb water and stops you from urinating. Without vasopressin, you end up going to the bathroom more and losing more water. While this might not be a big deal during happy hour, you'll certainly feel the effects of dehydration — headache, dry mouth, fatigue the next day.
With less water, the brain starts to contract, pulling on the nerves around it creating a massive headache. Your muscles, depleted of water and electrolytes, become sore and fatigued as if you’d overexerted them the day before. And as that water is streaming out of you it’s also pulling electrolytes like sodium, magnesium, calcium, and potassium out with it, which you need for normal muscle and nerve function.
Excerpts from: https://www.gotpurpletree.com/post/why-do-electrolytes-help-hangovers
Sources:
- Role of plasma vasopressin in changes of water balance accompanying acute alcohol intoxication
- Vasopressin and alcohol: a multifaceted relationship
- Effects of two different strategies of fluid administration on inflammatory mediators, plasma electrolytes and acid/base disorders in patients undergoing major abdominal surgery
- Electrolyte
- Influence of Hydration and Electrolyte Supplementation on Incidence and Time to Onset of Exercise-Associated Muscle Cramps
- High potassium intake increases the plasma concentration and urinary excretion of vasopressin in the rat
Hyaluronic Acid
Supports skin hydration and may reduce acid reflux.
Hydration
In case you’ve never noticed, there’s a direct correlation between the amount of alcohol you consume and the frequency of your trips to the bathroom. This is more than a mere coincidence.
Excessive consumption of alcohol decreases the production of Antidiuretic Hormone (ADH). The body uses it primarily to reabsorb water into the body tissues. Since alcohol suppresses its production your body ends up losing a lot of water through frequent urination.
Your skin contains molecules known as Hyaluronic Acid that are designed to capture and retain water deep beneath the skin surface. When these molecules get dehydrated you’ll start to notice wrinkles around your eye area, then your face, neck, and hands – generally, the areas of your body where your skin is thinnest. The body then attempts to combat this by secreting more sebum in the skin cells which in turn causes oily skin. You’ll see this manifest as blackheads, whiteheads, papules, and shine.
The more alcohol you consume over extended periods of time, the less Hyaluronic Acid your body produces, leading to the appearance of deep wrinkles.
Article Excerpts from: https://coastaldetox.com/surprising-effects-of-alcohol-on-skin-how-its-aging-you-inside-and-out/
Source:
Acid Reflux
New research shows hyaluronic acid supplements may help reduce symptoms of acid reflux.
When acid reflux occurs, the contents of the stomach are regurgitated up into the throat, causing pain and damage to the lining of the esophagus. Hyaluronic acid may help soothe the damaged lining of the esophagus and speed up the recovery process.
One test-tube study found that applying a mixture of hyaluronic acid and chondroitin sulfate to acid-damaged throat tissue helped it heal much faster than when no treatment was used.
Human studies have also shown benefits. One study found that taking a hyaluronic acid and chondroitin sulfate supplement along with an acid-reducing medication decreased reflux symptoms 60% more than taking acid-reducing medication alone.
A second study showed that the same type of supplement was five times more effective at reducing acid reflux symptoms than a placebo.
Sources:
- https://www.healthline.com/nutrition/hyaluronic-acid-benefits#TOC_TITLE_HDR_5
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347926/
- https://pubmed.ncbi.nlm.nih.gov/24379055/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387832/
Collagen
Promotes skin elasticity, strengthens hair and nails, and supports bone and joint health.
Sugary alcoholic beverages often also leads to loss of skin elasticity and the development of premature wrinkles.
Collagen is the most abundant protein in the body. It's found in all connective tissues in the tendons, ligaments muscles, as well as, you guessed it – the skin. It’s what gives your skin its structure. It’s what also slows down your skin’s aging process by reducing the appearance of wrinkles and the onset of dryness. But when you consume sugary drinks, the body rapidly converts this sugar into glucose, which in turn causes your insulin levels to spike as it works quickly to get rid of the glucose surge from the bloodstream. This spike causes a burst of inflammation throughout the body which produces enzymes that break down collagen.
Breaking down collagen prematurely contributes to the development of acne, dark patches and skin creases all over your body.
Collagen supplements (as well as hyaluronic acid supplements) battle these effects by reducing inflammation, improving your skin elasticity, and reducing wrinkles.
Article Excerpts from: https://coastaldetox.com/surprising-effects-of-alcohol-on-skin-how-its-aging-you-inside-and-out/
Source:
L-theanine
Found in green tea, it helps reduce stress and anxiety.
- L-theanine may alleviate uncomfortable symptoms due to alcohol, especially anxiety, which results from your brain overproducing glutamate, a chemical that causes anxiety and jitters.
- L-theanine may prevent alcoholic liver injury by enhancing antioxidant capability of liver cells.
- Alcohol use can increase the number of glutamate receptors (stress/ jitters receptors), which amino acids like L-theanine can fill to help prevent withdrawal symptoms (i.e., anxiety).
- In addition to its well-established relaxing effects, L-theanine has antipsychotic and antidepressant effects.
- L-theanine crosses the blood-brain barrier and exerts various effects, including increasing GABA activity, modulatingserotonin and dopamine, increasing brain-derived neurotrophic factor (BDNF), and increasing cognitive performance through its actions on NMDA receptors.
- Eight weeks of L-theanine administration to depressed patients produced multiple beneficial effects on depressive symptoms, anxiety, sleep disturbances, and cognitive impairments, according to studies.
- A study in mice found that L-theanine exerts a neuroprotective effect mediated by GABA-A receptors.
- L-theanine can help with nicotine withdrawal by significantly inhibiting the rewarding effects of nicotine, according to studies.
Sources:
- https://pubmed.ncbi.nlm.nih.gov/22019691/
- https://pubmed.ncbi.nlm.nih.gov/16141543/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2239014/
- https://pubmed.ncbi.nlm.nih.gov/21861094/
- https://pubmed.ncbi.nlm.nih.gov/23883567/
- https://pubmed.ncbi.nlm.nih.gov/27396868/
- https://pubmed.ncbi.nlm.nih.gov/17928735/
- https://pubmed.ncbi.nlm.nih.gov/23233221/
5-HTP (5-Hydroxytryptophan)
Helps boost serotonin to support increased happiness and lower anxiety
Influenced by alcohol, your brain produces extra serotonin and dopamine. These provide the kick you feel — improved mood and a higher sense of pleasure. Dopamine is the rewarding neurotransmitter and also the one that can make you feel wanting more. The increased serotonin temporarily makes you feel happy.
The day after a happy night out, as alcohol is being eliminated from your bloodstream, the neurotransmitter levels also get back to normal. The thing is though, that while alcohol gives a boost to your serotonin and dopamine levels, the next morning you will be deficient in these same chemicals, which may lead to you feeling down and anxious. In the long run, an excess of alcohol might cause long-term lower levels of serotonin causing depression and anxiety. (Article Excerpt from: https://medium.com/mind-cafe/feeling-blue-the-day-after-drinking-ca4a48b8d92d)
5-HTP is the natural precursor that the body uses to make serotonin, which means that 5-HTP taken as a supplement helps lead to increased serotonin levels in the brain which promotes relaxation, enhanced focus, improved sleep quality, and lower levels of anxiety and depression.
Sources:
- Jangid P, Malik P, Singh P, Sharma M, Gulia AK. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013
- Juki? T, Rojc B, Boben-Bardutzky D, Hafner M, Ihan A. The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. Coll Antropol. 2011
- Emanuele E, Bertona M, Minoretti P, Geroldi D. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress. Neuro Endocrinol Lett. 2010
- Iovieno N, Dalton ED, Fava M, Mischoulon D. Second-tier natural antidepressants: review and critique. J Affect Disord. 2011
- Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 2010
- Turner EH, Loftis JM, Blackwell AD. Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan. Pharmacol Ther. 2006
- Maron E, Tõru I, Vasar V, Shlik J. The effect of 5-hydroxytryptophan on cholecystokinin-4-induced panic attacks in healthy volunteers. J Psychopharmacol. 2004
- Das YT, Bagchi M, Bagchi D, Preuss HG. Safety of 5-hydroxy-L-tryptophan. Toxicol Lett. 2004
- Amer A, Breu J, McDermott J, Wurtman RJ, Maher TJ. 5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats. Pharmacol Biochem Behav. 2004
- Schruers K, van Diest R, Overbeek T, Griez E. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res. 2002
- Schruers K, van Diest R, Nicolson N, Griez E. L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers. Psychopharmacology (Berl). 2002
- Gijsman HJ, van Gerven JM, de Kam ML, Schoemaker RC, Pieters MS, Weemaes M, de Rijk R, van der Post J, Cohen AF. Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers. J Clin Psychopharmacol. 2002
- Shaw K, Turner J, Del Mar C. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev. 2002
- Ramaekers VT, Senderek J, Häusler M, Häring M, Abeling N, Zerres K, Bergmann C, Heimann G, Blau N. A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa. Mol Genet Metab. 2001
- Ribeiro CA. L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. For the Portuguese Head Society. Headache. 2000
- Meyers S. Use of neurotransmitter precursors for treatment of depression. Altern Med Rev. 2000
- Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev. 1998
- van Vliet IM, Slaap BR, Westenberg HG, Den Boer JA. Behavioral, neuroendocrine and biochemical effects of different doses of 5-HTP in panic disorder. Eur Neuropsychopharmacol. 1996
- Pöldinger W, Calanchini B, Schwarz W. A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine. Psychopathology. 1991